Search/Destroy Agents hunt the criminals too dangerous for the Galactic Crime Commission to control, living in the "Doghouse", a deep spaceport high above New Britain.
Humanity is at war with the technologically advanced Therians, a presumably robotic species bent on subjugating and transforming all planets for their ultimate purpose: the crafting of a "better", more organized universe under their rule, which they refer to as their "therian heaven".